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SMILES: Nc1nc2ccc(CN(CCC(O)=O)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key: InChIKey=KKNPESJUCXLSLY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024469   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Trifunctional purine biosynthetic protein adenosine-3


(Mus musculus)		BDBM50024469
PNG
(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Show SMILES Nc1nc2ccc(CN(CCC(O)=O)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)cc2c(=O)[nH]1
Show InChI InChI=1S/C24H25N5O8/c25-24-27-17-6-1-13(11-16(17)22(35)28-24)12-29(10-9-20(32)33)15-4-2-14(3-5-15)21(34)26-18(23(36)37)7-8-19(30)31/h1-6,11,18H,7-10,12H2,(H,26,34)(H,30,31)(H,32,33)(H,36,37)(H3,25,27,28,35)
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MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 3.20E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of GAR transformylase isolated from murine lymphoma cell line L5178Y

J Med Chem 30: 1254-6 (1987)


BindingDB Entry DOI: 10.7270/Q2VX0FHS
More data for this
Ligand-Target Pair