BDBM50024490 5-[Chloro-bis-(4-chloro-phenyl)-methyl]-pyrimidine::CHEMBL26208

SMILES: Clc1ccc(cc1)C(Cl)(c1ccc(Cl)cc1)c1cncnc1

InChI Key: InChIKey=KDFBFPOGRBLGMY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Rattus norvegicus)	BDBM50024490 (5-[Chloro-bis-(4-chloro-phenyl)-methyl]-pyrimidine...) Show SMILES Clc1ccc(cc1)C(Cl)(c1ccc(Cl)cc1)c1cncnc1 Show InChI InChI=1S/C17H11Cl3N2/c18-15-5-1-12(2-6-15)17(20,14-9-21-11-22-10-14)13-3-7-16(19)8-4-13/h1-11H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	275	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.				J Med Chem 30: 1359-65 (1987) BindingDB Entry DOI: 10.7270/Q2NP251P
					More data for this Ligand-Target Pair