BDBM50024580 CHEMBL3330612
SMILES: Cn1c(=O)cnn(CCCCN2CCN(CC2)c2ccccn2)c1=O
InChI Key: InChIKey=ZXGRMQACDGUTBN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50024580 (CHEMBL3330612) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from 5HT1AR (unknown origin) by competition binding assay | Bioorg Med Chem Lett 24: 4759-62 (2014) Article DOI: 10.1016/j.bmcl.2014.07.048 BindingDB Entry DOI: 10.7270/Q2NZ896M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50024580 (CHEMBL3330612) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Agonist activity at human 5HT1AR expressed in CHO cells assessed as increase in [35S]GTPgammaS binding by liquid scintillation spectrometry | Bioorg Med Chem Lett 24: 4759-62 (2014) Article DOI: 10.1016/j.bmcl.2014.07.048 BindingDB Entry DOI: 10.7270/Q2NZ896M | |||||||||||
More data for this Ligand-Target Pair |