BDBM50024934 7-Chloro-3-(3-imidazol-1-yl-2-methyl-propyl)-1H-quinazoline-2,4-dione; hydrochloride::CHEMBL544065::CHEMBL76234

SMILES: CC(Cn1ccnc1)Cn1c(=O)[nH]c2cc(Cl)ccc2c1=O

InChI Key: InChIKey=LBWJVMNHUULPIE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50024934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Rattus norvegicus)	BDBM50024934 (7-Chloro-3-(3-imidazol-1-yl-2-methyl-propyl)-1H-qu...) Show SMILES CC(Cn1ccnc1)Cn1c(=O)[nH]c2cc(Cl)ccc2c1=O Show InChI InChI=1S/C15H15ClN4O2/c1-10(7-19-5-4-17-9-19)8-20-14(21)12-3-2-11(16)6-13(12)18-15(20)22/h2-6,9-10H,7-8H2,1H3,(H,18,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Tested for inhibition of thromboxane synthetase from spontaneously hypertensive rats				J Med Chem 30: 2277-83 (1988) BindingDB Entry DOI: 10.7270/Q23T9HT6
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50024934 (7-Chloro-3-(3-imidazol-1-yl-2-methyl-propyl)-1H-qu...) Show SMILES CC(Cn1ccnc1)Cn1c(=O)[nH]c2cc(Cl)ccc2c1=O Show InChI InChI=1S/C15H15ClN4O2/c1-10(7-19-5-4-17-9-19)8-20-14(21)12-3-2-11(16)6-13(12)18-15(20)22/h2-6,9-10H,7-8H2,1H3,(H,18,22)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Division of American Cyanamid Company Curated by ChEMBL					Assay Description Tested for inhibition of thromboxane Synthetase from spontaneously hypertensive rats				J Med Chem 30: 2277-83 (1988) BindingDB Entry DOI: 10.7270/Q23T9HT6
					More data for this Ligand-Target Pair