BDBM50024998 CHEMBL3143412::CHEMBL436701::p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p5'(br8A)

SMILES: Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](COP(O)(=O)O[C@@H]6[C@H](O)[C@@H](CO)O[C@H]6n6c(Br)nc7c(N)ncnc67)O[C@H]5n5c(Br)nc6c(N)ncnc56)O[C@H]4n4c(Br)nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(Br)nc12

InChI Key: InChIKey=YNEFZBSRIXARAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50024998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Mus musculus)	BDBM50024998 (CHEMBL3143412 | p5'(br8A)2'p5'(br8A)2'p5'(br8A)2'p...) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](COP(O)(=O)O[C@@H]6[C@H](O)[C@@H](CO)O[C@H]6n6c(Br)nc7c(N)ncnc67)O[C@H]5n5c(Br)nc6c(N)ncnc56)O[C@H]4n4c(Br)nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(Br)nc12 |r| Show InChI InChI=1S/C40H46Br4N20O21P4/c41-37-57-22-26(45)49-9-53-30(22)61(37)21-4-16(65)20(82-21)8-78-89(73,74)85-19-3-15(81-36(19)64-33-25(60-40(64)44)29(48)52-12-56-33)7-77-88(71,72)84-18-2-14(80-35(18)63-32-24(59-39(63)43)28(47)51-11-55-32)6-76-87(69,70)83-17-1-13(5-75-86(66,67)68)79-34(17)62-31-23(58-38(62)42)27(46)50-10-54-31/h9-21,34-36,65H,1-8H2,(H,69,70)(H,71,72)(H,73,74)(H2,45,49,53)(H2,46,50,54)(H2,47,51,55)(H2,48,52,56)(H2,66,67,68)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description compound was tested for activation of RNase L by measuring concentration required for 50% inhibition of protein synthesis in mouse L cell extracts				J Med Chem 29: 1015-22 (1986) BindingDB Entry DOI: 10.7270/Q2SX6C6K
					More data for this Ligand-Target Pair