BDBM50025021 CHEMBL3337853

SMILES: FC1(F)Oc2cc3nc(NC(=O)c4cccc(c4)-c4nnn[nH]4)[nH]c3cc2O1

InChI Key: InChIKey=DRZUBQLBUDBSAP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50025021 (CHEMBL3337853) Show SMILES FC1(F)Oc2cc3nc(NC(=O)c4cccc(c4)-c4nnn[nH]4)[nH]c3cc2O1 Show InChI InChI=1S/C16H9F2N7O3/c17-16(18)27-11-5-9-10(6-12(11)28-16)20-15(19-9)21-14(26)8-3-1-2-7(4-8)13-22-24-25-23-13/h1-6H,(H2,19,20,21,26)(H,22,23,24,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of human recombinant CK1epsilon expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I delta (Rattus norvegicus (rat))	BDBM50025021 (CHEMBL3337853) Show SMILES FC1(F)Oc2cc3nc(NC(=O)c4cccc(c4)-c4nnn[nH]4)[nH]c3cc2O1 Show InChI InChI=1S/C16H9F2N7O3/c17-16(18)27-11-5-9-10(6-12(11)28-16)20-15(19-9)21-14(26)8-3-1-2-7(4-8)13-22-24-25-23-13/h1-6H,(H2,19,20,21,26)(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of rat CK1delta kinetic domain expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair
Casein kinase I delta (Rattus norvegicus (rat))	BDBM50025021 (CHEMBL3337853) Show SMILES FC1(F)Oc2cc3nc(NC(=O)c4cccc(c4)-c4nnn[nH]4)[nH]c3cc2O1 Show InChI InChI=1S/C16H9F2N7O3/c17-16(18)27-11-5-9-10(6-12(11)28-16)20-15(19-9)21-14(26)8-3-1-2-7(4-8)13-22-24-25-23-13/h1-6H,(H2,19,20,21,26)(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Ulm University Hospital Curated by ChEMBL					Assay Description Inhibition of GST-tagged rat CK1delta expressed in Escherichia coli using GST-p53 (1 to 64 residues) by SDS-PAGE based autoradiography				J Med Chem 57: 7933-46 (2014) Article DOI: 10.1021/jm500600b BindingDB Entry DOI: 10.7270/Q2N0183J
					More data for this Ligand-Target Pair