BDBM50025284 Acetic acid 2-acetoxy-5-(5,6,7-trimethoxy-4-oxo-4H-chromen-2-yl)-phenyl ester::CHEMBL72580

SMILES: COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(C)=O)c(OC(C)=O)c1

InChI Key: InChIKey=DPMAMVLUCQLSPL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50025284 (Acetic acid 2-acetoxy-5-(5,6,7-trimethoxy-4-oxo-4H...) Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OC)-c1ccc(OC(C)=O)c(OC(C)=O)c1 Show InChI InChI=1S/C22H20O9/c1-11(23)29-15-7-6-13(8-17(15)30-12(2)24)16-9-14(25)20-18(31-16)10-19(26-3)21(27-4)22(20)28-5/h6-10H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells.				J Med Chem 29: 2256-62 (1986) BindingDB Entry DOI: 10.7270/Q2M907P5
					More data for this Ligand-Target Pair