null

SMILES: CO[C@H]1CC[C@@H](CC1)NC(=O)c1n[nH]cc1NC(=O)Cc1ccccc1OC

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 alpha/beta (Homo sapiens (Human))	BDBM50025632 (CHEMBL3335122) Show SMILES CO[C@H]1CC[C@@H](CC1)NC(=O)c1n[nH]cc1NC(=O)Cc1ccccc1OC |r,wU:5.8,wD:2.1,(18.39,-5.49,;16.85,-5.48,;16.07,-6.81,;14.53,-6.8,;13.74,-8.13,;14.51,-9.46,;16.05,-9.47,;16.83,-8.15,;13.74,-10.79,;12.2,-10.78,;11.43,-9.45,;11.42,-12.12,;11.94,-13.57,;10.72,-14.51,;9.45,-13.64,;9.88,-12.16,;9.1,-10.84,;7.56,-10.86,;6.8,-12.2,;6.77,-9.53,;5.23,-9.55,;4.46,-8.22,;2.92,-8.24,;2.16,-9.58,;2.95,-10.91,;4.49,-10.89,;5.28,-12.21,;4.5,-13.55,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay				J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712
					More data for this Ligand-Target Pair