BDBM50025913 CHEMBL16457::[2-(Formyl-hydroxy-amino)-3-phenyl-propionylamino]-acetic acid

SMILES: ON(C=O)C(Cc1ccccc1)C(=O)NCC(O)=O

InChI Key: InChIKey=WNMKEMDPMUKVKU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50025913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50025913 (CHEMBL16457 | [2-(Formyl-hydroxy-amino)-3-phenyl-p...) Show SMILES ON(C=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-8-14(19)10(12(18)13-7-11(16)17)6-9-4-2-1-3-5-9/h1-5,8,10,19H,6-7H2,(H,13,18)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of enkephalinase purified from rat kidney.				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50025913 (CHEMBL16457 | [2-(Formyl-hydroxy-amino)-3-phenyl-p...) Show SMILES ON(C=O)C(Cc1ccccc1)C(=O)NCC(O)=O Show InChI InChI=1S/C12H14N2O5/c15-8-14(19)10(12(18)13-7-11(16)17)6-9-4-2-1-3-5-9/h1-5,8,10,19H,6-7H2,(H,13,18)(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair