BDBM50025915 CHEMBL16622::[2-Benzyl-3-(formyl-hydroxy-amino)-propionylamino]-acetic acid

SMILES: ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O

InChI Key: InChIKey=XWNIIJNUTOPWBP-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50025915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thermolysin (Bacillus thermoproteolyticus)	BDBM50025915 (CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...) Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Pohang University of Science and Technology Curated by ChEMBL					Assay Description Inhibitory activity against thermolysin using 2-furylacryloyl-Gly-Leu-NH2 as substrate at pH 7.2				Bioorg Med Chem Lett 8: 323-6 (1999) BindingDB Entry DOI: 10.7270/Q2WM1CJ0
					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50025915 (CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...) Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of enkephalinase purified from rat kidney.				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50025915 (CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...) Show SMILES ON(CC(Cc1ccccc1)C(=O)NCC(O)=O)C=O Show InChI InChI=1S/C13H16N2O5/c16-9-15(20)8-11(13(19)14-7-12(17)18)6-10-4-2-1-3-5-10/h1-5,9,11,20H,6-8H2,(H,14,19)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrate				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair