BDBM50025919 2-Benzyl-N-hydroxy-N'-[(3-methyl-butylcarbamoyl)-methyl]-malonamide::CHEMBL17084

SMILES: CC(C)CCNC(=O)CNC(=O)C(Cc1ccccc1)C(=O)NO

InChI Key: InChIKey=ZXDSFFOCXPBPSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50025919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50025919 (2-Benzyl-N-hydroxy-N'-[(3-methyl-butylcarbamoyl)-m...) Show SMILES CC(C)CCNC(=O)CNC(=O)C(Cc1ccccc1)C(=O)NO Show InChI InChI=1S/C17H25N3O4/c1-12(2)8-9-18-15(21)11-19-16(22)14(17(23)20-24)10-13-6-4-3-5-7-13/h3-7,12,14,24H,8-11H2,1-2H3,(H,18,21)(H,19,22)(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of enkephalinase purified from rat kidney.				J Med Chem 28: 1158-69 (1985) BindingDB Entry DOI: 10.7270/Q20C4WB5
					More data for this Ligand-Target Pair