BDBM50025936 CHEMBL3335253

SMILES: CCOc1cc(Br)c(Br)c(\C=N\c2ccc3[nH]cnc3c2)c1O

InChI Key: InChIKey=PVADOWMXYJMOMA-FBCYGCLPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50025936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BRK (Homo sapiens (Human))	BDBM50025936 (CHEMBL3335253) Show SMILES CCOc1cc(Br)c(Br)c(\C=N\c2ccc3[nH]cnc3c2)c1O Show InChI InChI=1S/C16H13Br2N3O2/c1-2-23-14-6-11(17)15(18)10(16(14)22)7-19-9-3-4-12-13(5-9)21-8-20-12/h3-8,22H,2H2,1H3,(H,20,21)/b19-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of PTK6 (unknown origin) expressed in HEK293 cells assessed as decrease in tyrosine phosphorylation by chemiluminescence assay				Bioorg Med Chem Lett 24: 4659-63 (2014) Article DOI: 10.1016/j.bmcl.2014.08.036 BindingDB Entry DOI: 10.7270/Q2TH8P84
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BRK (Homo sapiens (Human))	BDBM50025936 (CHEMBL3335253) Show SMILES CCOc1cc(Br)c(Br)c(\C=N\c2ccc3[nH]cnc3c2)c1O Show InChI InChI=1S/C16H13Br2N3O2/c1-2-23-14-6-11(17)15(18)10(16(14)22)7-19-9-3-4-12-13(5-9)21-8-20-12/h3-8,22H,2H2,1H3,(H,20,21)/b19-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of GST-tagged PTK6 (unknown origin) assessed as phosphorylated tyrosines after 20 mins by ELISA				Bioorg Med Chem Lett 24: 4659-63 (2014) Article DOI: 10.1016/j.bmcl.2014.08.036 BindingDB Entry DOI: 10.7270/Q2TH8P84
					More data for this Ligand-Target Pair