BDBM50026553 (+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(+/-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol (DP-5,6-ADTN)::CHEMBL11845

SMILES: CCCN(CCC)C1CCc2c(C1)ccc(O)c2O

InChI Key: InChIKey=JQHSYAQISCFWOK-UHFFFAOYSA-N

Data: 3 KI  5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50026553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Center for Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity of the compound towards Dopamine receptor D2				J Med Chem 46: 4136-40 (2003) Article DOI: 10.1021/jm0307786 BindingDB Entry DOI: 10.7270/Q2M61JP7
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Center for Pharmacy Curated by ChEMBL					Assay Description In vitro binding affinity of the compound towards Dopamine receptor D1				J Med Chem 46: 4136-40 (2003) Article DOI: 10.1021/jm0307786 BindingDB Entry DOI: 10.7270/Q2M61JP7
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description Tested for affinity against cloned mammalian dopamine autoreceptor (DA) D2 receptors expressed in CHO-K1 cells using [3H]spiperone as raidoligand				J Med Chem 37: 2735-53 (1994) BindingDB Entry DOI: 10.7270/Q2J96719
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar rats				J Med Chem 28: 679-83 (1985) BindingDB Entry DOI: 10.7270/Q2JW8H4K
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar rats				J Med Chem 28: 679-83 (1985) BindingDB Entry DOI: 10.7270/Q2JW8H4K
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...				J Med Chem 27: 495-503 (1984) BindingDB Entry DOI: 10.7270/Q24B31WH
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptors in striata of female wistar rats				J Med Chem 28: 679-83 (1985) BindingDB Entry DOI: 10.7270/Q2JW8H4K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
University Center for Pharmacy Curated by ChEMBL					Assay Description Tested for intrinsic activity of the compound towards Dopamine receptor D2 in CHO cells				J Med Chem 46: 4136-40 (2003) Article DOI: 10.1021/jm0307786 BindingDB Entry DOI: 10.7270/Q2M61JP7
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50026553 ((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...) Show SMILES CCCN(CCC)C1CCc2c(C1)ccc(O)c2O Show InChI InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of specific [3H]prazosin binding (0.2 nM) to rat brain membranes alpha-1 adrenergic receptor				J Med Chem 27: 495-503 (1984) BindingDB Entry DOI: 10.7270/Q24B31WH
					More data for this Ligand-Target Pair