BDBM50026562 CHEMBL23228::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-methyl-benzamide

SMILES: CCN1CCC[C@H]1CNC(=O)c1c(O)c(C)ccc1OC

InChI Key: InChIKey=UMEBCICPUODHSU-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50026562 (CHEMBL23228 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(C)ccc1OC Show InChI InChI=1S/C16H24N2O3/c1-4-18-9-5-6-12(18)10-17-16(20)14-13(21-3)8-7-11(2)15(14)19/h7-8,12,19H,4-6,9-10H2,1-3H3,(H,17,20)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membrane				J Med Chem 28: 1263-9 (1985) BindingDB Entry DOI: 10.7270/Q2QZ2BHD
					More data for this Ligand-Target Pair