BDBM50026563 CHEMBL22472::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-propyl-benzamide

SMILES: CCCc1ccc(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O

InChI Key: InChIKey=GXLRFNYVOBFUES-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50026563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50026563 (CHEMBL22472 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-...) Show SMILES CCCc1ccc(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O Show InChI InChI=1S/C18H28N2O3/c1-4-7-13-9-10-15(23-3)16(17(13)21)18(22)19-12-14-8-6-11-20(14)5-2/h9-10,14,21H,4-8,11-12H2,1-3H3,(H,19,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membrane				J Med Chem 28: 1263-9 (1985) BindingDB Entry DOI: 10.7270/Q2QZ2BHD
					More data for this Ligand-Target Pair