BDBM50026568 CHEMBL23464::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-iodo-2,6-dimethoxy-benzamide

SMILES: CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1OC

InChI Key: InChIKey=JJYGMNQCYKVCSO-NSHDSACASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50026568 (CHEMBL23464 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1OC Show InChI InChI=1S/C16H23IN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.676	n/a	n/a	n/a	n/a	n/a	n/a
University of Mazandaran Curated by ChEMBL					Assay Description Antagonist activity at dopamine D2 receptor				Eur J Med Chem 45: 4856-62 (2010) Article DOI: 10.1016/j.ejmech.2010.07.056 BindingDB Entry DOI: 10.7270/Q2833T8S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50026568 (CHEMBL23464 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1OC Show InChI InChI=1S/C16H23IN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membrane				J Med Chem 28: 1263-9 (1985) BindingDB Entry DOI: 10.7270/Q2QZ2BHD
					More data for this Ligand-Target Pair