BDBM50026573 CHEMBL3335313

SMILES: ONC(=O)CCCCCCCc1ccn(Cc2ccc(cc2)-c2ccccc2)n1

InChI Key: InChIKey=SUMJQFHPYSEIOM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50026573 (CHEMBL3335313) Show SMILES ONC(=O)CCCCCCCc1ccn(Cc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C24H29N3O2/c28-24(26-29)12-8-3-1-2-7-11-23-17-18-27(25-23)19-20-13-15-22(16-14-20)21-9-5-4-6-10-21/h4-6,9-10,13-18,29H,1-3,7-8,11-12,19H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 after 60 mins by fluorimetric assay				Eur J Med Chem 86: 639-52 (2014) Article DOI: 10.1016/j.ejmech.2014.09.024 BindingDB Entry DOI: 10.7270/Q2NV9KTB
					More data for this Ligand-Target Pair
Histone deacetylase 7 (Homo sapiens (Human))	BDBM50026573 (CHEMBL3335313) Show SMILES ONC(=O)CCCCCCCc1ccn(Cc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C24H29N3O2/c28-24(26-29)12-8-3-1-2-7-11-23-17-18-27(25-23)19-20-13-15-22(16-14-20)21-9-5-4-6-10-21/h4-6,9-10,13-18,29H,1-3,7-8,11-12,19H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC7 after 60 mins by fluorimetric assay				Eur J Med Chem 86: 639-52 (2014) Article DOI: 10.1016/j.ejmech.2014.09.024 BindingDB Entry DOI: 10.7270/Q2NV9KTB
					More data for this Ligand-Target Pair