BDBM50027015 2-Piperazin-1-yl-nicotinonitrile::CHEMBL48137

SMILES: N#Cc1cccnc1N1CCNCC1

InChI Key: InChIKey=QSMNQUURWIAXAA-UHFFFAOYSA-N

Data: 2 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cerebral cortex alpha adrenergic receptor (BOVINE)	BDBM50027015 (2-Piperazin-1-yl-nicotinonitrile | CHEMBL48137) Show SMILES N#Cc1cccnc1N1CCNCC1 Show InChI InChI=1S/C10H12N4/c11-8-9-2-1-3-13-10(9)14-6-4-12-5-7-14/h1-3,12H,4-7H2	PDB KEGG GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
					More data for this Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor (CALF)	BDBM50027015 (2-Piperazin-1-yl-nicotinonitrile | CHEMBL48137) Show SMILES N#Cc1cccnc1N1CCNCC1 Show InChI InChI=1S/C10H12N4/c11-8-9-2-1-3-13-10(9)14-6-4-12-5-7-14/h1-3,12H,4-7H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-1 adrenergic receptor from calf cerebral cortex, using [3H]-prazosin as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
					More data for this Ligand-Target Pair