BDBM50027033 CHEMBL541208::Cyclohexyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-p-tolyl-amine

SMILES: Cc1ccc(cc1)N(CC1=NCCN1)C1CCCCC1

InChI Key: InChIKey=CVOPKMOKCNOSBQ-UHFFFAOYSA-N

Data: 2 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50027033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
adrenergic Alpha2 (BOVINE)	BDBM50027033 (CHEMBL541208 | Cyclohexyl-(4,5-dihydro-1H-imidazol...) Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)C1CCCCC1 |t:10| Show InChI InChI=1S/C17H25N3/c1-14-7-9-16(10-8-14)20(13-17-18-11-12-19-17)15-5-3-2-4-6-15/h7-10,15H,2-6,11-13H2,1H3,(H,18,19)	KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]clonidine as the radioligand				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor (BOVINE)	BDBM50027033 (CHEMBL541208 | Cyclohexyl-(4,5-dihydro-1H-imidazol...) Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)C1CCCCC1 |t:10| Show InChI InChI=1S/C17H25N3/c1-14-7-9-16(10-8-14)20(13-17-18-11-12-19-17)15-5-3-2-4-6-15/h7-10,15H,2-6,11-13H2,1H3,(H,18,19)	KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	424	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligand				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50027033 (CHEMBL541208 | Cyclohexyl-(4,5-dihydro-1H-imidazol...) Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)C1CCCCC1 |t:10| Show InChI InChI=1S/C17H25N3/c1-14-7-9-16(10-8-14)20(13-17-18-11-12-19-17)15-5-3-2-4-6-15/h7-10,15H,2-6,11-13H2,1H3,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity against alpha-1 adrenergic receptor from rat vas deferens				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50027033 (CHEMBL541208 | Cyclohexyl-(4,5-dihydro-1H-imidazol...) Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)C1CCCCC1 |t:10| Show InChI InChI=1S/C17H25N3/c1-14-7-9-16(10-8-14)20(13-17-18-11-12-19-17)15-5-3-2-4-6-15/h7-10,15H,2-6,11-13H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from rats				J Med Chem 26: 1769-72 (1984) BindingDB Entry DOI: 10.7270/Q2668DRD
					More data for this Ligand-Target Pair