BDBM50027198 5-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-2,2-diphenyl-pentanenitrile::CHEMBL370660

SMILES: Clc1ccc(cc1)C1=CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1

InChI Key: InChIKey=SBTDSQSUVHMWSP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50027198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human herpesvirus 5 chemokine receptor (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM50027198 (5-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...) Show SMILES Clc1ccc(cc1)C1=CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1 |t:8| Show InChI InChI=1S/C28H27ClN2/c29-27-14-12-23(13-15-27)24-16-20-31(21-17-24)19-7-18-28(22-30,25-8-3-1-4-9-25)26-10-5-2-6-11-26/h1-6,8-16H,7,17-21H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by PDSP Ki Database					Assay Description Effective concentration against US28-mediated inositol phosphate production in COS-7 cells				J Med Chem 48: 6461-71 (2005) Article DOI: 10.1021/jm050418d BindingDB Entry DOI: 10.7270/Q2ZP4640
					More data for this Ligand-Target Pair
Human herpesvirus 5 chemokine receptor (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM50027198 (5-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...) Show SMILES Clc1ccc(cc1)C1=CCN(CCCC(C#N)(c2ccccc2)c2ccccc2)CC1 |t:8| Show InChI InChI=1S/C28H27ClN2/c29-27-14-12-23(13-15-27)24-16-20-31(21-17-24)19-7-18-28(22-30,25-8-3-1-4-9-25)26-10-5-2-6-11-26/h1-6,8-16H,7,17-21H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by PDSP Ki Database					Assay Description Inhibitory concentration against chemokine receptor US28 expressed in COS-7 cells using [125I]-CCL5				J Med Chem 48: 6461-71 (2005) Article DOI: 10.1021/jm050418d BindingDB Entry DOI: 10.7270/Q2ZP4640
					More data for this Ligand-Target Pair