Found 6 hits for monomerid = 50027241 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from human cloned mu opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from human cloned kappa opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from human cloned delta opioid receptor |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 133 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50027241
(CHEMBL2113299)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]51CC[C@]2(OC)[C@@H](CNC(=O)\C=C\c2ccc(cc2)[N+]([O-])=O)C1)ccc3OC |THB:10:9:5.4.6:14| Show InChI InChI=1S/C31H35N3O6/c1-33-15-14-30-26-20-7-10-23(38-2)27(26)40-28(30)31(39-3)13-12-29(30,24(33)16-20)17-21(31)18-32-25(35)11-6-19-4-8-22(9-5-19)34(36)37/h4-11,21,24,28H,12-18H2,1-3H3,(H,32,35)/b11-6+/t21-,24-,28-,29-,30+,31+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 214 | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description
Agonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding |
J Med Chem 50: 5176-82 (2007)
Article DOI: 10.1021/jm070255o
BindingDB Entry DOI: 10.7270/Q2RR202P |
More data for this
Ligand-Target Pair | |
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