BDBM50027605 1-[3-Benzoylsulfanyl-4-(3-fluoro-phenyl)-4-oxo-butyryl]-pyrrolidine-2-carboxylic acid::CHEMBL129572

SMILES: OC(=O)C1CCCN1C(=O)CC(SC(=O)c1ccccc1)C(=O)c1cccc(F)c1

InChI Key: InChIKey=WLGHXEUSLXKRDG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50027605 (1-[3-Benzoylsulfanyl-4-(3-fluoro-phenyl)-4-oxo-but...) Show SMILES OC(=O)C1CCCN1C(=O)CC(SC(=O)c1ccccc1)C(=O)c1cccc(F)c1 Show InChI InChI=1S/C22H20FNO5S/c23-16-9-4-8-15(12-16)20(26)18(30-22(29)14-6-2-1-3-7-14)13-19(25)24-11-5-10-17(24)21(27)28/h1-4,6-9,12,17-18H,5,10-11,13H2,(H,27,28)	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antihypertensive activity determined by inhibition of angiotensin I converting enzyme				J Med Chem 26: 381-93 (1983) BindingDB Entry DOI: 10.7270/Q2XS5VZQ
					More data for this Ligand-Target Pair