BDBM50027619 1-[3-Acetylsulfanyl-4-(4-bromo-phenyl)-2-methyl-4-oxo-butyryl]-pyrrolidine-2-carboxylic acid::CHEMBL128214

SMILES: C[C@H]([C@H](SC(C)=O)C(=O)c1ccc(Br)cc1)C(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=UWIBVAUAEBBHOQ-OOVXXXAESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50027619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50027619 (1-[3-Acetylsulfanyl-4-(4-bromo-phenyl)-2-methyl-4-...) Show SMILES C[C@H]([C@H](SC(C)=O)C(=O)c1ccc(Br)cc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C18H20BrNO5S/c1-10(17(23)20-9-3-4-14(20)18(24)25)16(26-11(2)21)15(22)12-5-7-13(19)8-6-12/h5-8,10,14,16H,3-4,9H2,1-2H3,(H,24,25)/t10-,14+,16+/m1/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro antihypertensive activity determined by inhibition of angiotensin I converting enzyme				J Med Chem 26: 381-93 (1983) BindingDB Entry DOI: 10.7270/Q2XS5VZQ
					More data for this Ligand-Target Pair