BDBM50027796 2-(Sulfanilylamino)thiazole::2-(p-Aminobenzenesulfonamido)thiazole::2-(p-Aminobenzenesulphonamido)thiazole::2-Sulfanilamidothiazol::2-Sulfanilamidothiazole::2-Sulfonamidothiazole::4-Amino-N-2-thiazolylbenzenesulfonamide::4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide::CHEMBL437::N(1)-2-Thiazolylsulfanilamide::Sulfanilamidothiazole::Sulfathiazole::Sulphathiazole::cid_5340
SMILES: Nc1ccc(cc1)S(=O)(=O)Nc1nccs1
InChI Key: InChIKey=JNMRHUJNCSQMMB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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exonuclease V (RecBCD complex), alpha chain (Escherichia coli str. K-12 substr. MG1655) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | 7.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q21G0JXG | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
EDNRA (RAT) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells. | J Med Chem 38: 1344-54 (1995) BindingDB Entry DOI: 10.7270/Q20864BS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcriptional activator protein lasR (Pseudomonas aeruginosa) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Inhibition of LasR in Pseudomonas aeruginosa harboring GFP-fused quorum sensing lasB measured every 15 mins up to 12 hrs by GFP reporter gene assay | J Med Chem 61: 10385-10402 (2018) Article DOI: 10.1021/acs.jmedchem.8b00540 BindingDB Entry DOI: 10.7270/Q2XP77NZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Prestwick Chemical Inc. Curated by ChEMBL | Assay Description Inhibitory concentration against Endothelin A receptor | J Med Chem 47: 1303-14 (2004) Article DOI: 10.1021/jm030480f BindingDB Entry DOI: 10.7270/Q2FN16X5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bacterial dihydropteroate synthase (Escherichia coli (strain K12)) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibition of dihydropteroate synthase from Escherichia coli. | J Med Chem 28: 1870-4 (1986) BindingDB Entry DOI: 10.7270/Q2542PRF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein arginine N-methyltransferase 6 (Homo sapiens (Human)) | BDBM50027796 (2-(Sulfanilylamino)thiazole | 2-(p-Aminobenzenesul...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 4.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto Curated by ChEMBL | Assay Description Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-... | J Med Chem 59: 1176-83 (2016) BindingDB Entry DOI: 10.7270/Q2SF2Z11 | |||||||||||
More data for this Ligand-Target Pair |