BDBM50028309 FOSMIDOMYCIN SODIUM::Fosmidomycin Sodium

SMILES: [Na+].ON(CCCP(O)([O-])=O)C=O

InChI Key: InChIKey=ZZPUYRHMTGOTEU-UHFFFAOYSA-M

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50028309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine Universit£t Curated by ChEMBL					Assay Description Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysis				J Med Chem 57: 8827-38 (2014) Article DOI: 10.1021/jm500850y BindingDB Entry DOI: 10.7270/Q2KP83RX
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (Plasmodium falciparum (isolate 3D7))	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum DXR assessed as reduction in NADPH oxidation in presence of DOXP by UV-visible spectrophotometry				J Med Chem 61: 8847-8858 (2018) Article DOI: 10.1021/acs.jmedchem.8b01026 BindingDB Entry DOI: 10.7270/Q2S75JZ7
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (Plasmodium falciparum (isolate 3D7))	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of recombinant Plasmodium falciparum IspC expressed in Escherichia coli using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric a...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.058
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli)	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.058
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis)	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by phot...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.058
					More data for this Ligand-Target Pair
1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic (Plasmodium falciparum (isolate 3D7))	BDBM50028309 (FOSMIDOMYCIN SODIUM | Fosmidomycin Sodium) Show SMILES [Na+].ON(CCCP(O)([O-])=O)C=O Show InChI InChI=1S/C4H10NO5P.Na/c6-4-5(7)2-1-3-11(8,9)10;/h4,7H,1-3H2,(H2,8,9,10);/q;+1/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
George Washington University Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum DXR				J Med Chem 61: 8847-8858 (2018) Article DOI: 10.1021/acs.jmedchem.8b01026 BindingDB Entry DOI: 10.7270/Q2S75JZ7
					More data for this Ligand-Target Pair