BDBM50028389 CHEMBL3342284

SMILES: [O-][N+](=O)c1ccc(CSc2ccc(cn2)C(=O)Nc2ccc(F)cc2)o1

InChI Key: InChIKey=LXIGTQOHFSELAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50028389 (CHEMBL3342284) Show SMILES [O-][N+](=O)c1ccc(CSc2ccc(cn2)C(=O)Nc2ccc(F)cc2)o1 Show InChI InChI=1S/C17H12FN3O4S/c18-12-2-4-13(5-3-12)20-17(22)11-1-7-15(19-9-11)26-10-14-6-8-16(25-14)21(23)24/h1-9H,10H2,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 in human PMNs assessed as inhibition of CXCL1-induced intracellular Ca2+ release by fluorescence based calcium flux assa...				J Med Chem 57: 8378-97 (2014) Article DOI: 10.1021/jm500827t BindingDB Entry DOI: 10.7270/Q2FX7C22
					More data for this Ligand-Target Pair