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SMILES: Fc1ccc(NC(=O)c2ccc(SC3CCOC3=O)nc2)cc1

InChI Key: InChIKey=ZREGDSVYDRWNER-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028405   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50028405
PNG
(CHEMBL3354644)
Show SMILES Fc1ccc(NC(=O)c2ccc(SC3CCOC3=O)nc2)cc1
Show InChI InChI=1S/C16H13FN2O3S/c17-11-2-4-12(5-3-11)19-15(20)10-1-6-14(18-9-10)23-13-7-8-22-16(13)21/h1-6,9,13H,7-8H2,(H,19,20)
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Similars
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Syntrix Biosystems

Curated by ChEMBL


Assay Description
Antagonist activity at CXCR2 in human PMNs assessed as inhibition of CXCL1-induced intracellular Ca2+ release by fluorescence based calcium flux assa...

J Med Chem 57: 8378-97 (2014)


Article DOI: 10.1021/jm500827t
BindingDB Entry DOI: 10.7270/Q2FX7C22
More data for this
Ligand-Target Pair