BDBM50028452 CHEMBL3335627

SMILES: OC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc3OCCOc3c2)c1

InChI Key: InChIKey=WYZLGIYUCJALHS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50028452 (CHEMBL3335627) Show SMILES OC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc3OCCOc3c2)c1 Show InChI InChI=1S/C23H18N2O6/c26-21(14-8-9-19-20(13-14)31-11-10-30-19)25-18-7-2-1-6-17(18)22(27)24-16-5-3-4-15(12-16)23(28)29/h1-9,12-13H,10-11H2,(H,24,27)(H,25,26)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Agonist activity at human FXR expressed in human HeLa cells assessed as receptor activation by BSEP promoter-driven firefly luciferase reporter gene ...				J Med Chem 57: 8035-55 (2014) Article DOI: 10.1021/jm500937v BindingDB Entry DOI: 10.7270/Q26H4K06
					More data for this Ligand-Target Pair