BDBM50028957 CHEMBL3360274

SMILES: CCc1nc2CC(C)(C)C[C@H](O)c2c2c1[C@H](OC21CCCC1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=MTUVDDPRZLURQM-WMZHIEFXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50028957 (CHEMBL3360274) Show SMILES CCc1nc2CC(C)(C)C[C@H](O)c2c2c1[C@H](OC21CCCC1)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C26H30F3NO2/c1-4-17-21-22(20-18(30-17)13-24(2,3)14-19(20)31)25(11-5-6-12-25)32-23(21)15-7-9-16(10-8-15)26(27,28)29/h7-10,19,23,31H,4-6,11-14H2,1-3H3/t19-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP by fluorescence transfer assay				J Med Chem 57: 8766-76 (2014) Article DOI: 10.1021/jm500431d BindingDB Entry DOI: 10.7270/Q2HT2QX3
					More data for this Ligand-Target Pair