Found 4 hits for monomerid = 50029079 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50029079
(CHEMBL3343273)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C20H19N3O2S/c21-26(24,25)19-10-6-16(7-11-19)12-14-22-15-17-4-8-18(9-5-17)20-3-1-2-13-23-20/h1-11,13,15H,12,14H2,(H2,21,24,25)/b22-15+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-9 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50029079
(CHEMBL3343273)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C20H19N3O2S/c21-26(24,25)19-10-6-16(7-11-19)12-14-22-15-17-4-8-18(9-5-17)20-3-1-2-13-23-20/h1-11,13,15H,12,14H2,(H2,21,24,25)/b22-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-12 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50029079
(CHEMBL3343273)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C20H19N3O2S/c21-26(24,25)19-10-6-16(7-11-19)12-14-22-15-17-4-8-18(9-5-17)20-3-1-2-13-23-20/h1-11,13,15H,12,14H2,(H2,21,24,25)/b22-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-2 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50029079
(CHEMBL3343273)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2ccc(cc2)-c2ccccn2)cc1 Show InChI InChI=1S/C20H19N3O2S/c21-26(24,25)19-10-6-16(7-11-19)12-14-22-15-17-4-8-18(9-5-17)20-3-1-2-13-23-20/h1-11,13,15H,12,14H2,(H2,21,24,25)/b22-15+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-1 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |