Found 4 hits for monomerid = 50029082 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50029082
(CHEMBL3343276)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2c[nH]c3ccc(Br)cc23)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c18-14-3-6-17-16(9-14)13(11-21-17)10-20-8-7-12-1-4-15(5-2-12)24(19,22)23/h1-6,9-11,21H,7-8H2,(H2,19,22,23)/b20-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-12 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50029082
(CHEMBL3343276)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2c[nH]c3ccc(Br)cc23)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c18-14-3-6-17-16(9-14)13(11-21-17)10-20-8-7-12-1-4-15(5-2-12)24(19,22)23/h1-6,9-11,21H,7-8H2,(H2,19,22,23)/b20-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 596 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-2 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50029082
(CHEMBL3343276)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2c[nH]c3ccc(Br)cc23)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c18-14-3-6-17-16(9-14)13(11-21-17)10-20-8-7-12-1-4-15(5-2-12)24(19,22)23/h1-6,9-11,21H,7-8H2,(H2,19,22,23)/b20-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-1 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50029082
(CHEMBL3343276)Show SMILES NS(=O)(=O)c1ccc(CC\N=C\c2c[nH]c3ccc(Br)cc23)cc1 Show InChI InChI=1S/C17H16BrN3O2S/c18-14-3-6-17-16(9-14)13(11-21-17)10-20-8-7-12-1-4-15(5-2-12)24(19,22)23/h1-6,9-11,21H,7-8H2,(H2,19,22,23)/b20-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human CA-9 after 15 mins by stopped-flow CO2 hydration method |
Bioorg Med Chem 22: 5883-90 (2014)
Article DOI: 10.1016/j.bmc.2014.09.021 BindingDB Entry DOI: 10.7270/Q2W097J5 |
More data for this Ligand-Target Pair | |