BDBM50029224 5,6-Dihydroxy-naphthalene-2-carboxylic acid methyl ester::CHEMBL18276

SMILES: COC(=O)c1ccc2c(O)c(O)ccc2c1

InChI Key: InChIKey=OHWJXNLECYLABW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50029224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50029224 (5,6-Dihydroxy-naphthalene-2-carboxylic acid methyl...) Show SMILES COC(=O)c1ccc2c(O)c(O)ccc2c1 Show InChI InChI=1S/C12H10O4/c1-16-12(15)8-2-4-9-7(6-8)3-5-10(13)11(9)14/h2-6,13-14H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against HIV-1 integrase.				J Med Chem 38: 4171-8 (1995) BindingDB Entry DOI: 10.7270/Q2SB44R7
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50029224 (5,6-Dihydroxy-naphthalene-2-carboxylic acid methyl...) Show SMILES COC(=O)c1ccc2c(O)c(O)ccc2c1 Show InChI InChI=1S/C12H10O4/c1-16-12(15)8-2-4-9-7(6-8)3-5-10(13)11(9)14/h2-6,13-14H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Ability to inhibit autophosphorylation of immunopurified p56Ick				J Med Chem 36: 425-32 (1993) BindingDB Entry DOI: 10.7270/Q2CV4GTQ
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50029224 (5,6-Dihydroxy-naphthalene-2-carboxylic acid methyl...) Show SMILES COC(=O)c1ccc2c(O)c(O)ccc2c1 Show InChI InChI=1S/C12H10O4/c1-16-12(15)8-2-4-9-7(6-8)3-5-10(13)11(9)14/h2-6,13-14H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase-mediated 3'-processing				J Med Chem 40: 1186-94 (1997) Article DOI: 10.1021/jm960449w BindingDB Entry DOI: 10.7270/Q2M044H3
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50029224 (5,6-Dihydroxy-naphthalene-2-carboxylic acid methyl...) Show SMILES COC(=O)c1ccc2c(O)c(O)ccc2c1 Show InChI InChI=1S/C12H10O4/c1-16-12(15)8-2-4-9-7(6-8)3-5-10(13)11(9)14/h2-6,13-14H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase-mediated strand transfer				J Med Chem 40: 1186-94 (1997) Article DOI: 10.1021/jm960449w BindingDB Entry DOI: 10.7270/Q2M044H3
					More data for this Ligand-Target Pair