BDBM50029424 (3aR,4R)-4-(4-Methoxy-phenyl)-2,3,3a,4-tetrahydro-benzo[b]pyrrolo[1,2-d][1,4]thiazin-1-one::CHEMBL139134

SMILES: COc1ccc(cc1)[C@H]1Sc2ccccc2N2[C@@H]1CCC2=O

InChI Key: InChIKey=YVAWKMIGJCZPDD-CRAIPNDOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM50029424 ((3aR,4R)-4-(4-Methoxy-phenyl)-2,3,3a,4-tetrahydro-...) Show SMILES COc1ccc(cc1)[C@H]1Sc2ccccc2N2[C@@H]1CCC2=O Show InChI InChI=1S/C18H17NO2S/c1-21-13-8-6-12(7-9-13)18-15-10-11-17(20)19(15)14-4-2-3-5-16(14)22-18/h2-9,15,18H,10-11H2,1H3/t15-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Siena Curated by ChEMBL					Assay Description Calcium antagonistic activity by measuring [3H]-nitrendipine displacement from rat heart L-type [Ca2+] channel				J Med Chem 38: 4393-410 (1995) BindingDB Entry DOI: 10.7270/Q24M93JW
					More data for this Ligand-Target Pair