BDBM50029522 4-Hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10,11-hexahydro-5H-cyclonona[b]pyran-2-one::CHEMBL132747
SMILES: CCC(c1ccccc1)c1c(O)c2CCCCCCCc2oc1=O
InChI Key: InChIKey=UMPZHMBRNGYJAP-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1) | BDBM50029522 (4-Hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10,11-hexahy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn Laboratories Curated by ChEMBL | Assay Description Inhibitory activity against HIV-I protease. | J Med Chem 38: 4463-73 (1995) BindingDB Entry DOI: 10.7270/Q2MP529V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 protease (Human immunodeficiency virus type 1) | BDBM50029522 (4-Hydroxy-3-(1-phenyl-propyl)-6,7,8,9,10,11-hexahy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia and Upjohn Curated by ChEMBL | Assay Description Binding affinity of the compound towards HIV protease was determined | J Med Chem 39: 4125-30 (1996) Article DOI: 10.1021/jm960296c BindingDB Entry DOI: 10.7270/Q2KH0MFB | |||||||||||
More data for this Ligand-Target Pair |