BDBM50029893 2-[4-Butyl-5-(2'-carboxy-biphenyl-4-ylmethyl)-2-methyl-6-oxo-6H-pyrimidin-1-ylmethyl]-furan-3-carboxylic acid::CHEMBL343840

SMILES: CCCCc1nc(C)n(Cc2occc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=UQNYGNPOKQTLGL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029893   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II type 1a (AT-1a) receptor (Bos taurus)	BDBM50029893 (2-[4-Butyl-5-(2'-carboxy-biphenyl-4-ylmethyl)-2-me...) Show SMILES CCCCc1nc(C)n(Cc2occc2C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C29H28N2O6/c1-3-4-9-25-24(27(32)31(18(2)30-25)17-26-23(29(35)36)14-15-37-26)16-19-10-12-20(13-11-19)21-7-5-6-8-22(21)28(33)34/h5-8,10-15H,3-4,9,16-17H2,1-2H3,(H,33,34)(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Lusofarmaco Curated by ChEMBL					Assay Description Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive				J Med Chem 38: 4806-20 (1996) BindingDB Entry DOI: 10.7270/Q2JQ101N
					More data for this Ligand-Target Pair