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BDBM50029897 4'-[4-Butyl-1-(4-carboxy-benzyl)-6-oxo-1,6-dihydro-pyrimidin-5-ylmethyl]-biphenyl-2-carboxylic acid::CHEMBL146164

SMILES: CCCCc1ncn(Cc2ccc(cc2)C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=QDEPHLBJBBXYHQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50029897   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor


(Bos taurus)		BDBM50029897
PNG
(4'-[4-Butyl-1-(4-carboxy-benzyl)-6-oxo-1,6-dihydro...)
Show SMILES CCCCc1ncn(Cc2ccc(cc2)C(O)=O)c(=O)c1Cc1ccc(cc1)-c1ccccc1C(O)=O
Show InChI InChI=1S/C30H28N2O5/c1-2-3-8-27-26(28(33)32(19-31-27)18-21-11-15-23(16-12-21)29(34)35)17-20-9-13-22(14-10-20)24-6-4-5-7-25(24)30(36)37/h4-7,9-16,19H,2-3,8,17-18H2,1H3,(H,34,35)(H,36,37)
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PubMed
>4n/an/an/an/an/an/an/an/a



Istituto Lusofarmaco

Curated by ChEMBL


Assay Description
Binding affinity towards Angiotensin II type 2 receptor in bovine cerebellar cortical membranes; Inactive

J Med Chem 38: 4806-20 (1996)


BindingDB Entry DOI: 10.7270/Q2JQ101N
More data for this
Ligand-Target Pair