BDBM50029935 6-(1-Benzyl-piperidin-4-ylmethyl)-6,7,8,9-tetrahydro-benzocyclohepten-5-one::CHEMBL344317

SMILES: O=C1C(CC2CCN(Cc3ccccc3)CC2)CCCc2ccccc12

InChI Key: InChIKey=SKJAMKPPTBWOCF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Mus musculus (mouse))	BDBM50029935 (6-(1-Benzyl-piperidin-4-ylmethyl)-6,7,8,9-tetrahyd...) Show SMILES O=C1C(CC2CCN(Cc3ccccc3)CC2)CCCc2ccccc12 Show InChI InChI=1S/C24H29NO/c26-24-22(11-6-10-21-9-4-5-12-23(21)24)17-19-13-15-25(16-14-19)18-20-7-2-1-3-8-20/h1-5,7-9,12,19,22H,6,10-11,13-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against acetylcholinesterase				J Med Chem 38: 4821-9 (1996) BindingDB Entry DOI: 10.7270/Q2QC045T
					More data for this Ligand-Target Pair
Acetylcholinesterase (Mus musculus (mouse))	BDBM50029935 (6-(1-Benzyl-piperidin-4-ylmethyl)-6,7,8,9-tetrahyd...) Show SMILES O=C1C(CC2CCN(Cc3ccccc3)CC2)CCCc2ccccc12 Show InChI InChI=1S/C24H29NO/c26-24-22(11-6-10-21-9-4-5-12-23(21)24)17-19-13-15-25(16-14-19)18-20-7-2-1-3-8-20/h1-5,7-9,12,19,22H,6,10-11,13-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acetylcholinesterase activity in mouse brain homogenate				Bioorg Med Chem Lett 2: 871-876 (1992) Article DOI: 10.1016/S0960-894X(00)80547-8 BindingDB Entry DOI: 10.7270/Q21R6QDV
					More data for this Ligand-Target Pair