null

SMILES: Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12

InChI Key: InChIKey=RGMGLZVBKZSCTM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50030625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50030625 (CHEMBL3354137) Show SMILES Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C17H14N2O5S/c1-11-9-16(20)24-15-10-12(7-8-14(11)15)18-17(21)19-25(22,23)13-5-3-2-4-6-13/h2-10H,1H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50030625 (CHEMBL3354137) Show SMILES Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C17H14N2O5S/c1-11-9-16(20)24-15-10-12(7-8-14(11)15)18-17(21)19-25(22,23)13-5-3-2-4-6-13/h2-10H,1H3,(H2,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50030625 (CHEMBL3354137) Show SMILES Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C17H14N2O5S/c1-11-9-16(20)24-15-10-12(7-8-14(11)15)18-17(21)19-25(22,23)13-5-3-2-4-6-13/h2-10H,1H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50030625 (CHEMBL3354137) Show SMILES Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 Show InChI InChI=1S/C17H14N2O5S/c1-11-9-16(20)24-15-10-12(7-8-14(11)15)18-17(21)19-25(22,23)13-5-3-2-4-6-13/h2-10H,1H3,(H2,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method				J Med Chem 57: 9152-67 (2014) Article DOI: 10.1021/jm501314c BindingDB Entry DOI: 10.7270/Q2CV4K97
					More data for this Ligand-Target Pair