BDBM50031009 1-(2-Hydroxy-ethoxymethyl)-5-(3-isobutoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL445839

SMILES: CC(C)COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1

InChI Key: InChIKey=AXDCZCJENGHNOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine phosphorylase 1 (Mus musculus)	BDBM50031009 (1-(2-Hydroxy-ethoxymethyl)-5-(3-isobutoxy-benzyl)-...) Show SMILES CC(C)COc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 Show InChI InChI=1S/C18H24N2O5/c1-13(2)11-25-16-5-3-4-14(9-16)8-15-10-20(12-24-7-6-21)18(23)19-17(15)22/h3-5,9-10,13,21H,6-8,11-12H2,1-2H3,(H,19,22,23)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair