BDBM50031074 3-(furan-2-yl)-5H-indeno[1,2-c]pyridazin-5-one::3-Furan-2-yl-indeno[1,2-c]pyridazin-5-one::CHEMBL420523

SMILES: O=C1c2ccccc2-c2nnc(cc12)-c1ccco1

InChI Key: InChIKey=UGGFLMWYLHAWIG-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031074 (3-(furan-2-yl)-5H-indeno[1,2-c]pyridazin-5-one | 3...) Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccco1 Show InChI InChI=1S/C15H8N2O2/c18-15-10-5-2-1-4-9(10)14-11(15)8-12(16-17-14)13-6-3-7-19-13/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase B enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50031074 (3-(furan-2-yl)-5H-indeno[1,2-c]pyridazin-5-one | 3...) Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccco1 Show InChI InChI=1S/C15H8N2O2/c18-15-10-5-2-1-4-9(10)14-11(15)8-12(16-17-14)13-6-3-7-19-13/h1-8H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of human supersomes MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031074 (3-(furan-2-yl)-5H-indeno[1,2-c]pyridazin-5-one | 3...) Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccco1 Show InChI InChI=1S/C15H8N2O2/c18-15-10-5-2-1-4-9(10)14-11(15)8-12(16-17-14)13-6-3-7-19-13/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50031074 (3-(furan-2-yl)-5H-indeno[1,2-c]pyridazin-5-one | 3...) Show SMILES O=C1c2ccccc2-c2nnc(cc12)-c1ccco1 Show InChI InChI=1S/C15H8N2O2/c18-15-10-5-2-1-4-9(10)14-11(15)8-12(16-17-14)13-6-3-7-19-13/h1-8H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase A enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair