BDBM50031179 (S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentanoic acid m-tolylamide::CHEMBL129140

SMILES: CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1

InChI Key: InChIKey=YCUUSGPXPIBQIQ-RLSDIYDTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50031179 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C16H27N3OS/c1-4-12(3)15(18-9-13(17)10-21)16(20)19-14-7-5-6-11(2)8-14/h5-8,12-13,15,18,21H,4,9-10,17H2,1-3H3,(H,19,20)/t12?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Geranylgeranyl Transferase (GGTase-I) (Bos taurus (bovine))	BDBM50031179 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C16H27N3OS/c1-4-12(3)15(18-9-13(17)10-21)16(20)19-14-7-5-6-11(2)8-14/h5-8,12-13,15,18,21H,4,9-10,17H2,1-3H3,(H,19,20)/t12?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair