BDBM50031306 8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(4',5'-dihydro[1,3]oxazole)]-2'-amine::CHEMBL133231
SMILES: NC1=NC2(CO1)CCc1cccc(Cl)c1C2
InChI Key: InChIKey=OAXNLMLMEYQSSS-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50031306 (8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Binding affinity towards Alpha-2A adrenergic receptor in human platelets using [3H]-RX-821002 as radioligand | J Med Chem 38: 4056-69 (1995) BindingDB Entry DOI: 10.7270/Q2DV1HXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (NEONATAL RAT) | BDBM50031306 (8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Binding affinity towards Alpha-2B adrenergic receptor in neonatal rat lung using [3H]-RX-821002 as radioligand | J Med Chem 38: 4056-69 (1995) BindingDB Entry DOI: 10.7270/Q2DV1HXN | |||||||||||
More data for this Ligand-Target Pair |