| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
|---|
| Ligand | BDBM50031306 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_33501 (CHEMBL647000) |
|---|
| Ki | 20±n/a nM |
|---|
| Citation |  Cordi, AA; Lacoste, JM; Descombes, JJ; Courchay, C; Vanhoutte, PM; Laubie, M; Verbeuren, TJ Design, synthesis, and structure-activity relationships of a new series of alpha-adrenergic agonists: spiro[(1,3-diazacyclopent-1-ene)-5,2'-(1',2',3',4'- tetrahydronaphthalene)]. J Med Chem38:4056-69 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2B adrenergic receptor |
|---|
| Name: | Alpha-2B adrenergic receptor |
|---|
| Synonyms: | ADA2B_RAT | Adra2b | Adrenergic receptor alpha | Adrenergic receptor alpha-2 | Alpha-2B adrenergic receptor | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | adrenergic Alpha2B |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 50379.83 |
|---|
| Organism: | NEONATAL RAT |
|---|
| Description: | adrenergic Alpha2B ADRA2B NEONATAL RAT::P19328 |
|---|
| Residue: | 453 |
|---|
| Sequence: | MSGPTMDHQEPYSVQATAAIASAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLA
AADILVATLIIPFSLANELLGYWYFWRAWCEVYLALDVLFCTSSIVHLCAISLDRYWAVS
RALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQRPEPRGLPQCELNQEAWYILA
SSIGSFFAPCLIMILVYLRIYVIAKRSHCRGLGAKRGSGEGESKKPQPVAGGVPTSAKVP
TLVSPLSSVGEANGHPKPPREKEEGETPEDPEARALPPTWSALPRSGQGQKKGTSGATAE
EGDEEDEEEVEECEPQTLPASPASVCNPPLQQPQTSRVLATLRGQVLLGKNVGVASGQWW
RRRTQLSREKRFTFVLAVVIGVFVVCWFPFFFSYSLGAICPQHCKVPHGLFQFFFWIGYC
NSSLNPVIYTVFNQDFRRAFRRILCRPWTQTGW
|
|
|
|---|
| BDBM50031306 |
|---|
| n/a |
|---|
| Name | BDBM50031306 |
|---|
| Synonyms: | 8-chlorospiro[1,2,3,4-tetrahydronaphthalene-2,4'-(4',5'-dihydro[1,3]oxazole)]-2'-amine | CHEMBL133231 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H13ClN2O |
|---|
| Mol. Mass. | 236.697 |
|---|
| SMILES | NC1=NC2(CO1)CCc1cccc(Cl)c1C2 |t:1| |
|---|
| Structure | 
|
|---|
Search and Browse
