BDBM50031483 (2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrrolidine-3,4-diol::CHEMBL310231
SMILES: CN1[C@H](CO)[C@@H](O)[C@H](O)[C@H]1CO
InChI Key: InChIKey=YWBPEHFIHKFMMC-DBRKOABJSA-N
Data: 8 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Maltase-glucoamylase (Homo sapiens (Human)) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Glycosidases (maltase) in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method maltase | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trehalase (Rattus norvegicus) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Glycosidases (trehalase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat)) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannosidase 2, alpha B1 (Rattus norvegicus) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of lysosomal Alpha-mannosidase II in rat liver | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lactase-glycosylceramidase (Rattus norvegicus) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Glycosidases (lactase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat)) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of Glycosidases (isomaltase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mannosidase 2 alpha 1 (Rattus norvegicus) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | <5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of golgi Alpha-mannosidase II in rat liver | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-mannosidase 2C1 (Rattus norvegicus) | BDBM50031483 ((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University Curated by ChEMBL | Assay Description Inhibition of soluble Alpha-mannosidase II in rat liver | J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0 | |||||||||||
More data for this Ligand-Target Pair |