Found 3 hits for monomerid = 50031500 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 4
(Mus musculus) | BDBM50031500
(CHEMBL2372859)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O |wU:52.54,12.12,4.3,66.70,wD:20.20,30.31,41.43,(28.22,-.04,;26.88,-.81,;25.55,-.04,;24.22,-.81,;22.88,-.04,;22.88,1.5,;24.22,2.27,;25.55,1.5,;24.22,3.81,;21.55,-.81,;21.55,-2.35,;20.22,-.04,;18.88,-.81,;18.88,-2.35,;17.55,-3.12,;16.21,-2.35,;17.55,-4.66,;17.55,-.04,;17.55,1.5,;16.21,-.81,;14.88,-.04,;14.88,1.5,;13.55,2.27,;12.14,1.64,;11.11,2.78,;11.88,4.12,;13.39,3.8,;13.55,-.81,;13.55,-2.35,;12.21,-.04,;10.88,-.81,;10.88,-2.35,;9.55,-3.12,;9.55,-4.66,;8.21,-5.43,;6.88,-4.66,;6.88,-3.12,;8.21,-2.35,;9.55,-.04,;9.55,1.5,;8.21,-.81,;6.88,-.04,;6.88,1.5,;8.21,2.27,;8.21,3.81,;9.55,4.58,;9.55,6.12,;8.21,6.89,;10.88,6.89,;5.55,-.81,;5.55,-2.35,;4.21,-.04,;2.88,-.81,;2.88,-2.35,;1.54,-3.12,;.14,-2.5,;-.89,-3.64,;-.12,-4.98,;-.6,-6.44,;.43,-7.58,;1.94,-7.26,;2.41,-5.8,;1.38,-4.66,;1.54,-.04,;1.54,1.5,;.21,-.81,;-1.12,-.04,;-2.46,-.81,;-3.79,-.04,;-5.12,-.81,;-6.46,-.04,;-7.79,-.81,;-1.12,1.5,;-2.46,2.27,;.21,2.27,)| Show InChI InChI=1S/C50H71N15O10/c1-3-4-16-36(59-29(2)66)44(70)65-41(25-42(67)68)49(75)64-40(24-32-27-55-28-58-32)48(74)62-38(22-30-13-6-5-7-14-30)46(72)61-37(19-12-21-56-50(53)54)45(71)63-39(23-31-26-57-34-17-9-8-15-33(31)34)47(73)60-35(43(52)69)18-10-11-20-51/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25,51H2,1-2H3,(H2,52,69)(H,55,58)(H,59,66)(H,60,73)(H,61,72)(H,62,74)(H,63,71)(H,64,75)(H,65,70)(H,67,68)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a |
University of Cergy-Pontoise
Curated by ChEMBL
| Assay Description
Activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
J Med Chem 57: 9424-34 (2014)
Article DOI: 10.1021/jm501027w
BindingDB Entry DOI: 10.7270/Q21G0NVT |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50031500
(CHEMBL2372859)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O |wU:52.54,12.12,4.3,66.70,wD:20.20,30.31,41.43,(28.22,-.04,;26.88,-.81,;25.55,-.04,;24.22,-.81,;22.88,-.04,;22.88,1.5,;24.22,2.27,;25.55,1.5,;24.22,3.81,;21.55,-.81,;21.55,-2.35,;20.22,-.04,;18.88,-.81,;18.88,-2.35,;17.55,-3.12,;16.21,-2.35,;17.55,-4.66,;17.55,-.04,;17.55,1.5,;16.21,-.81,;14.88,-.04,;14.88,1.5,;13.55,2.27,;12.14,1.64,;11.11,2.78,;11.88,4.12,;13.39,3.8,;13.55,-.81,;13.55,-2.35,;12.21,-.04,;10.88,-.81,;10.88,-2.35,;9.55,-3.12,;9.55,-4.66,;8.21,-5.43,;6.88,-4.66,;6.88,-3.12,;8.21,-2.35,;9.55,-.04,;9.55,1.5,;8.21,-.81,;6.88,-.04,;6.88,1.5,;8.21,2.27,;8.21,3.81,;9.55,4.58,;9.55,6.12,;8.21,6.89,;10.88,6.89,;5.55,-.81,;5.55,-2.35,;4.21,-.04,;2.88,-.81,;2.88,-2.35,;1.54,-3.12,;.14,-2.5,;-.89,-3.64,;-.12,-4.98,;-.6,-6.44,;.43,-7.58,;1.94,-7.26,;2.41,-5.8,;1.38,-4.66,;1.54,-.04,;1.54,1.5,;.21,-.81,;-1.12,-.04,;-2.46,-.81,;-3.79,-.04,;-5.12,-.81,;-6.46,-.04,;-7.79,-.81,;-1.12,1.5,;-2.46,2.27,;.21,2.27,)| Show InChI InChI=1S/C50H71N15O10/c1-3-4-16-36(59-29(2)66)44(70)65-41(25-42(67)68)49(75)64-40(24-32-27-55-28-58-32)48(74)62-38(22-30-13-6-5-7-14-30)46(72)61-37(19-12-21-56-50(53)54)45(71)63-39(23-31-26-57-34-17-9-8-15-33(31)34)47(73)60-35(43(52)69)18-10-11-20-51/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25,51H2,1-2H3,(H2,52,69)(H,55,58)(H,59,66)(H,60,73)(H,61,72)(H,62,74)(H,63,71)(H,64,75)(H,65,70)(H,67,68)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
University of Cergy-Pontoise
Curated by ChEMBL
| Assay Description
Activity at mouse MC3R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
J Med Chem 57: 9424-34 (2014)
Article DOI: 10.1021/jm501027w
BindingDB Entry DOI: 10.7270/Q21G0NVT |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50031500
(CHEMBL2372859)Show SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O |wU:52.54,12.12,4.3,66.70,wD:20.20,30.31,41.43,(28.22,-.04,;26.88,-.81,;25.55,-.04,;24.22,-.81,;22.88,-.04,;22.88,1.5,;24.22,2.27,;25.55,1.5,;24.22,3.81,;21.55,-.81,;21.55,-2.35,;20.22,-.04,;18.88,-.81,;18.88,-2.35,;17.55,-3.12,;16.21,-2.35,;17.55,-4.66,;17.55,-.04,;17.55,1.5,;16.21,-.81,;14.88,-.04,;14.88,1.5,;13.55,2.27,;12.14,1.64,;11.11,2.78,;11.88,4.12,;13.39,3.8,;13.55,-.81,;13.55,-2.35,;12.21,-.04,;10.88,-.81,;10.88,-2.35,;9.55,-3.12,;9.55,-4.66,;8.21,-5.43,;6.88,-4.66,;6.88,-3.12,;8.21,-2.35,;9.55,-.04,;9.55,1.5,;8.21,-.81,;6.88,-.04,;6.88,1.5,;8.21,2.27,;8.21,3.81,;9.55,4.58,;9.55,6.12,;8.21,6.89,;10.88,6.89,;5.55,-.81,;5.55,-2.35,;4.21,-.04,;2.88,-.81,;2.88,-2.35,;1.54,-3.12,;.14,-2.5,;-.89,-3.64,;-.12,-4.98,;-.6,-6.44,;.43,-7.58,;1.94,-7.26,;2.41,-5.8,;1.38,-4.66,;1.54,-.04,;1.54,1.5,;.21,-.81,;-1.12,-.04,;-2.46,-.81,;-3.79,-.04,;-5.12,-.81,;-6.46,-.04,;-7.79,-.81,;-1.12,1.5,;-2.46,2.27,;.21,2.27,)| Show InChI InChI=1S/C50H71N15O10/c1-3-4-16-36(59-29(2)66)44(70)65-41(25-42(67)68)49(75)64-40(24-32-27-55-28-58-32)48(74)62-38(22-30-13-6-5-7-14-30)46(72)61-37(19-12-21-56-50(53)54)45(71)63-39(23-31-26-57-34-17-9-8-15-33(31)34)47(73)60-35(43(52)69)18-10-11-20-51/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25,51H2,1-2H3,(H2,52,69)(H,55,58)(H,59,66)(H,60,73)(H,61,72)(H,62,74)(H,63,71)(H,64,75)(H,65,70)(H,67,68)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | n/a |
University of Cergy-Pontoise
Curated by ChEMBL
| Assay Description
Activity at mouse MC1R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assay |
J Med Chem 57: 9424-34 (2014)
Article DOI: 10.1021/jm501027w
BindingDB Entry DOI: 10.7270/Q21G0NVT |
More data for this
Ligand-Target Pair | |
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