BDBM50031643 1-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-propenone; hydrochloride::CHEMBL552859
SMILES: CN(C)CC(=C)C(=O)c1ccc(OCc2ccccc2)cc1
InChI Key: InChIKey=HXXAYPIGMDAGIS-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50031643 (1-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-prope...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA Limited Curated by ChEMBL | Assay Description In vitro inhibition of the Epidermal growth factor receptor activity in A431 membranes | J Med Chem 38: 2441-8 (1995) BindingDB Entry DOI: 10.7270/Q2MS3TDK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50031643 (1-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-prope...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA Limited Curated by ChEMBL | Assay Description In vitro inhibition of the c-src tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrate | J Med Chem 38: 2441-8 (1995) BindingDB Entry DOI: 10.7270/Q2MS3TDK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50031643 (1-(4-Benzyloxy-phenyl)-2-dimethylaminomethyl-prope...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA Limited Curated by ChEMBL | Assay Description In vitro inhibition of the v-abl tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrate | J Med Chem 38: 2441-8 (1995) BindingDB Entry DOI: 10.7270/Q2MS3TDK | |||||||||||
More data for this Ligand-Target Pair |