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BDBM50031948 2-Butyl-5-chloro-3-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethyl]-3H-imidazole-4-carbaldehyde::CHEMBL315881

SMILES: CCCCc1nc(Cl)c(C=O)n1Cc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1

InChI Key: InChIKey=ZRNTZASSCRYQEQ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031948   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50031948
PNG
(2-Butyl-5-chloro-3-[5-oxo-11-(1H-tetrazol-5-yl)-5H...)
Show SMILES CCCCc1nc(Cl)c(C=O)n1Cc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1
Show InChI InChI=1S/C25H21ClN6O2/c1-2-3-8-22-27-24(26)21(14-33)32(22)13-15-9-10-18-19(11-15)23(34)17-7-5-4-6-16(17)12-20(18)25-28-30-31-29-25/h4-7,9-12,14H,2-3,8,13H2,1H3,(H,28,29,30,31)
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PC cid
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12n/an/an/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1


J Med Chem 38: 2728-41 (1995)


BindingDB Entry DOI: 10.7270/Q23B5Z5Q
More data for this
Ligand-Target Pair