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BDBM50031965 2-Ethyl-4-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethoxy]-quinoline-6-carboxylic acid::CHEMBL330508

SMILES: CCc1cc(OCc2ccc3c(cc4ccccc4c(=O)c3c2)-c2nnn[nH]2)c2cc(ccc2n1)C(O)=O

InChI Key: InChIKey=XBDRFPZAQGCRSX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50031965
PNG
(2-Ethyl-4-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dibenzo[...)
Show SMILES CCc1cc(OCc2ccc3c(cc4ccccc4c(=O)c3c2)-c2nnn[nH]2)c2cc(ccc2n1)C(O)=O
Show InChI InChI=1S/C29H21N5O4/c1-2-19-14-26(24-13-18(29(36)37)8-10-25(24)30-19)38-15-16-7-9-21-22(11-16)27(35)20-6-4-3-5-17(20)12-23(21)28-31-33-34-32-28/h3-14H,2,15H2,1H3,(H,36,37)(H,31,32,33,34)
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PC cid
PC sid
UniChem
PubMed
2.70n/an/an/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1


J Med Chem 38: 2728-41 (1995)


BindingDB Entry DOI: 10.7270/Q23B5Z5Q
More data for this
Ligand-Target Pair