BDBM50032225 5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-propenyl]-thiophene-3-carboxylic acid::CHEMBL93628

SMILES: C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C

InChI Key: InChIKey=ZEDKEKWGCXBKCJ-NTEUORMPSA-N

Data: 9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50032225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR gamma				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR alpha				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	201	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoid X receptor RXR alpha				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	>0.00100	n/a	n/a	n/a	n/a
Allergan, Inc Curated by ChEMBL					Assay Description Transcriptional activation of Retinoic acid receptor RAR beta				J Med Chem 38: 2820-9 (1995) BindingDB Entry DOI: 10.7270/Q2FN157S
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	979	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RAR gamma in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RAR beta in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RXR beta in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RXR alpha in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50032225 (5-[(E)-2-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...) Show SMILES C\C(=C/c1cc(cs1)C(O)=O)c1cc2c(cc1C)C(C)(C)CCC2(C)C Show InChI InChI=1S/C23H28O2S/c1-14(9-17-11-16(13-26-17)21(24)25)18-12-20-19(10-15(18)2)22(3,4)7-8-23(20,5)6/h9-13H,7-8H2,1-6H3,(H,24,25)/b14-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity for retinoic acid receptor RXR gamma in transcriptional activation assay				Bioorg Med Chem Lett 5: 2729-2734 (1995) Article DOI: 10.1016/0960-894X(95)00455-3 BindingDB Entry DOI: 10.7270/Q22N527N
					More data for this Ligand-Target Pair