BDBM50032567 Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL78375

SMILES: O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12

InChI Key: InChIKey=MITVBOWRUQYOMP-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50032567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor (Rattus norvegicus (rat))	BDBM50032567 (Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12 Show InChI InChI=1S/C23H22N2O3/c26-22(19-6-3-4-17-8-13-28-23(17)19)20-16-25(21-7-2-1-5-18(20)21)10-9-24-11-14-27-15-12-24/h1-8,13,16H,9-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bioorganic & Petroleum Chemistry Curated by ChEMBL					Assay Description Binding affinity at cannabinoid receptor 1 using rat brain membranes				J Med Chem 44: 2411-20 (2001) Article DOI: 10.1021/jm010858e BindingDB Entry DOI: 10.7270/Q2GT5QXX
					More data for this Ligand-Target Pair
Cannabinoid receptor (Rattus norvegicus (rat))	BDBM50032567 (Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12 Show InChI InChI=1S/C23H22N2O3/c26-22(19-6-3-4-17-8-13-28-23(17)19)20-16-25(21-7-2-1-5-18(20)21)10-9-24-11-14-27-15-12-24/h1-8,13,16H,9-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.82E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Division Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from Cannabinoid receptor 1 of rat forebrain membranes				J Med Chem 41: 4521-32 (1998) Article DOI: 10.1021/jm980305c BindingDB Entry DOI: 10.7270/Q2XD14F0
					More data for this Ligand-Target Pair
Cannabinoid receptor (Rattus norvegicus (rat))	BDBM50032567 (Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12 Show InChI InChI=1S/C23H22N2O3/c26-22(19-6-3-4-17-8-13-28-23(17)19)20-16-25(21-7-2-1-5-18(20)21)10-9-24-11-14-27-15-12-24/h1-8,13,16H,9-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.08E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bioorganic & Petroleum Chemistry Curated by ChEMBL					Assay Description Binding affinity at cannabinoid receptor 1 using rat brain membranes				J Med Chem 44: 2411-20 (2001) Article DOI: 10.1021/jm010858e BindingDB Entry DOI: 10.7270/Q2GT5QXX
					More data for this Ligand-Target Pair
Cannabinoid receptor (Rattus norvegicus (rat))	BDBM50032567 (Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12 Show InChI InChI=1S/C23H22N2O3/c26-22(19-6-3-4-17-8-13-28-23(17)19)20-16-25(21-7-2-1-5-18(20)21)10-9-24-11-14-27-15-12-24/h1-8,13,16H,9-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.08E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Division Curated by ChEMBL					Assay Description Cannabinoid receptor 1 binding affinity by measuring its ability to displace [3H]WIN-55212-2 in rat forebrain membranes				J Med Chem 41: 4521-32 (1998) Article DOI: 10.1021/jm980305c BindingDB Entry DOI: 10.7270/Q2XD14F0
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50032567 (Benzofuran-7-yl-[1-(2-morpholin-4-yl-ethyl)-1H-ind...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccoc12 Show InChI InChI=1S/C23H22N2O3/c26-22(19-6-3-4-17-8-13-28-23(17)19)20-16-25(21-7-2-1-5-18(20)21)10-9-24-11-14-27-15-12-24/h1-8,13,16H,9-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Research Division Curated by ChEMBL					Assay Description Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.				J Med Chem 38: 3094-105 (1995) BindingDB Entry DOI: 10.7270/Q2DN442Z
					More data for this Ligand-Target Pair